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Relationship Between Candida Albicans and Lactobacilli in Oral Flora

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dc.contributor.author Parvaresh, Shahrzad
dc.date.accessioned 2019-06-07T16:12:16Z
dc.date.available 2019-06-07T16:12:16Z
dc.date.issued 1981-10-06
dc.identifier.citation S. Parvaresh, "Relationship Between Candida Albicans and Lactobacilli in Oral Flora", Thesis, School of Arts & Sciences, Univ. of Bridgeport, Bridgeport, CT, 1981. en_US
dc.identifier.uri https://scholarworks.bridgeport.edu/xmlui/handle/123456789/4178
dc.description This thesis is being archived as a Digitized Shelf Copy for campus access to current students and staff only. We currently cannot provide this open access without the author's permission. If you are the author of this work and desire to provide it open access or wish access removed please contact the Wahlstrom Library to discuss permission. en_US
dc.description.abstract Candida albicans and Lactobacillus spp. coexist on mucous membranes at a number of sites in the human body. It has been reported that lactobacilli exhibit an inhibitory effect on Candida albicans. Since both organisms can be found in the oral cavity, their relationship to each other was investigated using salivary samples. Preliminary work involved the determination of the two organism's distributions in 139 healthy college students aged 18-27. Distribution was correlated with salivary pH and oral hygiene habits of the students. Both organisms were cultured from 29% of the samples, and Lactobacillus spp. alone were cultured from 30%. There appeared to be a positive correlation between increasing pH and the presence of Candida albicans. Subsequent studies were carried out on isolated organisms. These included the determination of the effect of both Lactobacillus cells and cell extracts on the growth of Candida albicans, and its susceptibility to amphotericin B. No significant effect of Lactobacillus spp. on Candida albicans could be detected in vitro. It is suggested that the interrelationships of these organisms may manifest themselves in competition for colonization sites on the mucous membranes. This hypothesis could be tested using either live animals or tissue culture cells. en_US
dc.language.iso en_US en_US
dc.subject Candida Albicans en_US
dc.subject Lactobacilli en_US
dc.title Relationship Between Candida Albicans and Lactobacilli in Oral Flora en_US
dc.type Thesis en_US
dc.institute.department School of Arts and Sciences en_US
dc.institute.name University of Bridgeport en_US

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