Abstract:
Cell counting (such as white blood cells, red blood cells) is a popular technique being used in blood testing for disease diagnosis. It can give important indication about the health condition of a patient, and give hints for doctors to effectively diagnose disease. In this poster, a BioMEMS (Bio-Microelectromechanical Systems) cell counter with concurrent processing is proposed. It has presorting stage to separate out red blood cells, white blood cells and/or other cells of interest from the microfluidic flow of blood sample. The cells are then passed to branching stage to divide it into multiple braches. Each branch allows cells to pass through the microchannel in series. The cell counting is achieved by electrical impedance sensing. By introducing concurrent counting based on branching, it leads to faster throughput and improved efficiency. The proposed BioMEMS cell counter is designed and simulated in COMSOL. Simulation results verified the correct counting function of the cell counter device.