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Separation and Characterization of Cells with Varying Magnetic Nanoparticle Concentration

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dc.contributor.author Choudhury, Ishita
dc.contributor.author Patra, Prabir
dc.contributor.author Petryk, Alicia
dc.date.accessioned 2018-04-23T15:38:22Z
dc.date.available 2018-04-23T15:38:22Z
dc.date.issued 2018-03-23
dc.identifier.uri https://scholarworks.bridgeport.edu/xmlui/handle/123456789/2198
dc.description.abstract The activation of magnetic nanoparticles (mNPs) by an alternating magnetic field (AMF) is currently being explored as technique for targeted therapeutic heating of tumors. Engineered nanoparticles have attracted much attention during the last decade because of their size-related properties, large surface-to-volume ratios and high surface reactivity. Parameters such as the size, charge and surface chemistry are examined because they affect the interactions of the nanoparticles with living cells. The mechanism for the uptake and distribution within cells is not fully understood. Optimization of targeted cellular uptake is critical if many nanoparticle-based applications are to become utilized in the clinical and research settings. We propose to develop a method to separate cells based on intracellular mNP concentration which will enable further study and optimization of cellular uptake in tumor cells. en_US
dc.language.iso en_US en_US
dc.subject Cells en_US
dc.subject Magnetic nanoparticles en_US
dc.title Separation and Characterization of Cells with Varying Magnetic Nanoparticle Concentration en_US
dc.type Other en_US
dc.institute.department School of Engineering en_US
dc.institute.name University of Bridgeport en_US
dc.event.location Bridgeport, CT en_US
dc.event.name Faculty Research Day en_US

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