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Effect of Microgravity on Nanoparticle-Cellular Interaction

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dc.contributor.author Juliano, Emily
dc.contributor.author Djoule, Feissal
dc.contributor.author Macwan, Isaac
dc.date.accessioned 2018-04-13T14:35:25Z
dc.date.available 2018-04-13T14:35:25Z
dc.date.issued 2018-03-23
dc.identifier.uri https://scholarworks.bridgeport.edu/xmlui/handle/123456789/2176
dc.description Faculty Research Day 2018: Student Spaceflight Experiments Program Winning Experiment en_US
dc.description Faculty Research Day 2018: Undergraduate Student Poster 1st Place en_US
dc.description.abstract A cell contains numerous proteins on its surface and in the cytoplasm that carry out a variety of functions. Maleimide – functionalized Graphene quantum dots (m-GQDs) have the ability to attach or “tag” both cell surface and intracellular proteins in the gravitational setting. Such quantum dots have photoluminescent properties, which can be utilized for tagging the cysteine residue on the proteins and hence in the bio-imaging applications of these proteins. This experiment proposes whether m-GQDs will have a stable binding to cellular proteins on Chinese Hamster Ovary (CHO) mammalian cells under the influence of microgravity. If this occurs, it can provide a wide variety of applications for studying the effects of micro gravity on a physiological system in the way proteins behave compared to a gravitational setting. The basic principle of this procedure can be further utilized to study many more cellular processes under the influence of microgravity by simply tracking these “tagged” cellular proteins under a fluorescence microscope. en_US
dc.language.iso en_US en_US
dc.subject Cells en_US
dc.subject Graphene quantum dots en_US
dc.subject Maleimide en_US
dc.subject Microgravity en_US
dc.title Effect of Microgravity on Nanoparticle-Cellular Interaction en_US
dc.type Other en_US
dc.institute.department School of Engineering en_US
dc.institute.name University of Bridgeport en_US
dc.event.location Bridgeport, CT en_US
dc.event.name Faculty Research Day en_US

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