Can the actions on regulatory T cells by natural substances influence the expression of T helper subsets, and therefore overall immune function?
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Authors
Robinson, Matthew
Issue Date
2013
Type
Thesis
Language
en_US
Keywords
Naturopathy , T helper cells , Regulatory T helper cells (Tregs) , Foxp3 , Transcription factors , Cytokines , Tolerance , Natural substances , Vitamins , Minerals , Herbs , Probiotics , Omega-3 Essential Fatty Acids , Autoimmune disease , Allergy , Atopy
Alternative Title
Abstract
Regulatory T helper cells (Tregs) play an important role in promoting tolerance among T helper subsets. Research was conducted to determine if any natural substances had demonstrable effects on Treg function, and additionally if that effect could result in positive changes in chronic immune diseases such as autoimmunity or allergy. A search of the available literature revealed many natural substances to have demonstrated effects on Treg function through epigenetic, cell signaling, and unknown mechanisms. The potential for treatment of autoimmune and allergic conditions through the use of natural substances that act on Tregs shows great promise and should be studied further.
Description
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Citation
M. Robinson, "Can the actions on regulatory T cells by natural substances influence the expression of T helper subsets, and therefore overall immune function?", ND dissertation, College of Naturopathic Medicine, Univ. of Bridgeport, Bridgeport, CT, 2013.