Abnormalities of IL-6 in Autism: A Literature Review
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Authors
Panza, Elise
Issue Date
2014
Type
Thesis
Language
en_US
Keywords
Naturopathy , Autism , Interleukin 6 (IL-6)
Alternative Title
Abstract
The purpose of this review is to assess the evidence for whether IL-6 elevation is present in autism, particularly within the CNS, and to evaluate the neuroanatomical and behavioral implications of elevated IL-6, and more broadly, neuroinflammation. Maternal immune activation is explored as a plausible pathogenetic mechanism for IL-6 elevation as well as the presence of autistic behaviors. The effects of IL-6 on gene expression are investigated in relation to the JAK-STAT pathway.
Description
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Citation
E. Panza, "Abnormalities of IL-6 in Autism: A Literature Review", ND dissertation, College of Naturopathic Medicine, Univ. of Bridgeport, Bridgeport, CT, 2014.