The interaction of Moringa Oleifera with Chromium and the effect on Chinese Hamster Ovary cell toxicity
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Authors
Palacio, Sara
Issue Date
2021-04-09
Type
Other
Language
en_US
Keywords
Cell toxicity , Chinese hamster ovary , Moringa oleifera
Alternative Title
Abstract
Moringa oleifera is a plant with countless nutritional and therapeutic properties, and it is considered as one of the supplements that prevent diseases because of its antioxidant effects. In this study, treatment of CHO (Chinese Hamster Ovary) cells with commercially available M. oleifera (900 µg/ml, 4 mg/ml, 9 mg/ml, and 17.5 mg/ml) induced cytotoxic effects. Furthermore, cells were treated with different concentrations of chromium (0.25, 0.5, and 1 µM) combined with M. oleifera extract to evaluate its protective effect against heavy metals. Statistical analyses indicated that M. oleifera extract is toxic to the cells in a dose-dependent manner. Therefore, our results suggest that chromium reduces the toxicity of M. oleifera by increasing cell viability. These observations suggest that chromium may antagonize the toxicity M. oleifera extracts and acts as a protective agent to cell toxicity.