Brain Health & Healthy Aging
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Authors
Ciolfi, Michael
Issue Date
2026-04-17
Type
Other
Language
en_US
Keywords
Brain health , Aging , Dementia
Alternative Title
Abstract
Dementia was first recognized as a condition of aged individuals as early as the 7th century BCE by the Greeks. By the mid-19th century, dementia was identified as its own class of mental disorder. The turn of the 20th century included advanced histochemical stains applied to brain tissue revealing widespread plaques, abnormal cytoskeletal changes within neurons, glial cells, and neuronal death that included plaques and tangles. Alois Alzheimer used advanced staining techniques to discover amyloid plaques and neurofibrillary tangles in a middle-aged woman in 1906. The extent of the pathologies throughout the brain were correlated with the extent of the dementia exhibited by the individual. Dementia is a detrimental neurodegenerative condition that is affecting every country on earth as the globe experiences increased levels of population aging.
Description
UB Rise 2026
College of Health Sciences