COMSOL Simulation of a BioMEMS Disease-diagnostic Lab-on-a-Chip Device
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Authors
Zou, Junyi
Xiong, Xingguo
Hu, Junling
Patra, Prabir
Issue Date
2015-03-27
Type
Presentation
Language
en_US
Keywords
Bio-micro-electro-mechanical-systems (BioMEMS) , Disease diagnostic system
Alternative Title
Abstract
Efficient, portable and accurate Disease Diagnostic systems are in great demand for modern clinical testing industry. Such systems are especially needed for patients with complicated health conditions. For example, some patients may have a variety of diseases, conventional testing methods may not be able to check it out all at once. In case of an emergency, failure to accurately determine the cause could be fatal for the patients. In this poster, a complete lab-on-a-chip device for disease diagnosis based on BioMEMS (Bio-Micro-Electro-Mechanical-Systems) technology is proposed. The proposed efficient disease diagnosis system integrates micropump, micromixer and gel electrophoresis component into a single chip. An on-chip control circuitry is used to store the pre-programmed blood sampling, buffering and chemical delivery sequence. Based on the theoretical analysis, a set of optimized design parameters of the lab-on-chip system are suggested. The working principle of the efficient disease diagnostic system is discussed. COMSOL simulation is used to verify the function of the system. The proposed efficient disease diagnostic system offers excellent efficiency, accuracy and portability compared to traditional disease diagnostic procedure. If integrated with other testing chips, it could provide a useful tool for biomedical field and be crucial for micro total analysis system.