The role of cognitive behavioral therapy, antidepressants, and anxiolytics on patients with IBS and comorbid anxiety or depression: A Review
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Authors
Russo, Karlee
Issue Date
2026-04-17
Type
Other
Language
en_US
Keywords
Cognitive behavioral therapy , Anxiety , Antidepressants
Alternative Title
Abstract
This literature review examines the role of cognitive behavioral therapy (CBT), antidepressants, and anxiolytics in alleviating gastrointestinal symptoms in patients with irritable bowel syndrome (IBS) who also have comorbid anxiety or depression. IBS is a functional gastrointestinal disorder significantly influenced by the gut-brain axis, making this an important and promising area of research. The aim of this review is to evaluate current research on the efficacy of CBT, antidepressants, and anxiolytics in managing IBS symptoms. A total of 20 studies were reviewed, and the findings suggest that these interventions can improve both gastrointestinal symptom and overall quality of life. However, further research is necessary before these treatments can be widely adopted in standard clinical practice. At present, medical providers should not routinely recommend the use of CBT or antidepressants/anxiolytics for the treatment of IBS in patients with comorbid psychiatric conditions.
Description
UB Rise 2026
University of Bridgeport Physician Assistant Institute