L-Glutamine Use In The Treatment And Prevention Of Mucositis And Cachexia: A Naturopathic Perspective
No Thumbnail Available
Authors
Noe, Jody E.
Issue Date
2009-12-29
Type
Article
Language
Keywords
Integrative treatment , Mucositis , Stomatitis , Cachexia , Diarrhea , Systemic diseases , Gastrointestinal system , Cancer treatment
Alternative Title
Abstract
L-Glutamine (L-GLN) is considered a nonessential amino acid that has a variety of applications in naturopathic medicine. It has been postulated that in the critically ill patient, GLN becomes an essential amino acid for recovery, restoration, and repair at a cellular level. Mucositis is an intestinal mucosal damage of the gastrointestinal tract—mouth, throat, stomach, intestines, rectum, and anus-that is caused directly by chemotherapies and radiotherapies. Cancer cachexia is a significant biochemical event, which is characterized by weight loss, fatigue, and indicative of depletion of skeletal muscle GLN-a hypercatabolic state. There has been some question as to the use of GLN in this patient population because of its role as a preferred energy source not only for enterocytes and lymphocytes but for malignant cells as well. This article will address the questions of safety, efficacy, dosing, and toxicity of GLN used as an integrative therapeutic in ongoing integrative cancer treatment.
Description
This is an article on the topic, there is also a poster from this author by the same title.
Citation
Noe JE. L-Glutamine Use In The Treatment And Prevention Of Mucositis And Cachexia: A Naturopathic Perspective. Integrative Cancer Therapies. December 2009; 8(4)
Publisher
SAGE Publishers