Length Dependent Interactions of Carbon Nanotubes and Surfactant Protein B
Loading...
Authors
Wu, Qi
Issue Date
2018-03-23
Type
Other
Language
en_US
Keywords
Carbon nanotubes , Surfactant protein B
Alternative Title
Abstract
Molecule dynamics (MD) simulation is a powerful computational tool to study the interaction between two or more molecules. In this poster, we present the interaction of carbon nanotubes (CNT) with surfactant protein B (SPB). SPB is a member of pulmonary surfactant protein family, which contributes to maintain alveolar surface tension. The lack of pulmonary surface tension will lead to collapse of alveoli in infants. This is the leading cause of infant respiratory distress syndrome (IRDS). To develop CNT based biosensor, study of these interactions between sensor material (CNT) and protein (SPB) at atomic level is very important. In practical situation, many protein molecules may surround the sensing element CNT. In this case, protein adsorption on CNT is influenced by CNT-proteins and protein-protein interactions. In addition, different lengths of CNTs also affect the rate of protein adsorption on CNT surface. Results show, as the length of CNT increases also increasing the specific surface area we see greater protein adsorption rate. All protein molecules experience different degrees of conformation change to achieve their stable state on CNT surface.